What is in painkillers and anti-depressants that make for a deadly combination?

Question

What is in painkillers and anti-depressants that make for a deadly combination?

Answer 1

If your using them correctly, its not

But many people over use them, and its a deadly amount of the same drug

Follow your doctors orders and you wouldn't have anything to worry about

Answer 2

Anything in access is a deadly combo.  Your question scares me.  I hope you are OK.

Answer 3

It's not using them together, it is overusing them.  A lot of pain killers lose their affect and you have to use more to get the same affect. That's where the danger comes in.

Answer 4

Um....I have no idea what you are talking about. I took painkillers while on antidepressants...in fact my doctor encouraged me to do so because one of their common side effects was headaches.

Answer 5

The classic example of such a lethal combination is the concomitant use of Demerol and an MAO-Inhibitor.

Answer 6

central nervous system depression, slows breathing, heart rate, etc.

That's not normally a deadly combo though, painkillers and benzodiazopines are! Benzo's such as valium and painkillers such as hydrocodone are a horrible combo in high doses.