What is protein kinase c?

Question

What is protein kinase c?

Answer 1

In simple words:

One subgroup of protein kinases is protein kinase C, which catalyze the phosphorylation of tyrosine residues in certain proteins.

hope this helps or use wikipedia for more information:

http://en.wikipedia.org/wiki/Protein_kin...

Answer 2

The answer above is incorrect only in one detail - protein kinase C does not phosphorylate tyrosine residues - it's a protein serine/threonine kinase.

There is a family of related protein kinase C genes, but the enzyme referred to as protein kinase C was originally discovered by virtue of its ability to be activated by phorbol ester tumor promoters.  In a cell, this common and abundant protein kinase is activated by diacyglycerol and membrane phospholipids, in the presence of elevated calcium.  Some subtypes of protein kinase C do not require the elevated calcium, and are simply lipid-activated.