What is the difference between Hodgkins Lymphoma and Non-Hodgkins Lymphoma, Please help me out?

Question

In immunological cancer

Answer 1

Please see the web page for Comparison of Hodgkin Lymphoma and Non-Hodgkin Lymphoma

Answer 2

Hi,

Lymphoma has two main forms – Hodgkin’s Lymphoma and Non-Hodgkin’s Lymphoma.

Hodgkin’s lymphoma / Hodgkin’s disease (HD) – is a cancer of a certain kind of lymphatic cell, the Reed-Sternberg cell which is a large abnormal white blood cell. When this cell is detected in a sample from the lymph node, the diagnosis for Hodgkin’s disease is confirmed. It occurs in adolescents and young adults and is distinguished from the other form of lymphomas only by the presence of the abnormal cell. This disease is the more curable form out of all lymphomas.

Non-Hodgkin’s lymphoma (NHL) – also called lymphosarcoma, this is a disease that originates in one type of lymph tissue – either in the lymph nodes, spleen, bone marrow or any of the other tissues. In NHL, a certain type of white blood cell is affected. These could be the cells that make defending proteins, or those that have natural killing properties. The disease is classified on the basis of how fast it grows. Very fast growing NHL is considered high-grade while the slow growing form is classified as low-grade.

The symptoms are:

Both the types of lymphomas have some common symptoms:

Enlarged but painless lymph nodes

Fatigue

Weight loss

Unexplained fevers

Sweating at night

Some symptoms more common in HD are enlarged liver and spleen, chest pain due to blockage in the blood vessels, difficulty in breathing and skin rashes. Other symptoms more common in NHL are signs of anaemia, tendency to bruise and bleed easily, pain in the bones and increased risk of infections.

The diagnosis

Lymphoma is diagnosed by biopsies where a tissue sample is tested for abnormalities. If the presence of the Reed-Sternberg cell is detected, HD is confirmed. The various biopsies that are done are from the bone marrow, lymph nodes and the cancerous mass of cells. In addition, blood tests including CBC (complete blood count) are done. X-rays of the suspected area are studied. Since the disease spreads in stages, moving from one lymph node to a lymphatic tissue and finally to the whole body, CT scans of the affected area are taken.

Answer 3

alot, google it or read it in a book smart guy

Answer 4

It starts with local, painless swelling of lymph nodes and sometimes of the spleen, liver, or other organs, followed by weight loss and weakness. Diagnosis can be confirmed only by biopsy, usually from a lymph node. The cause remains unknown. Treatment with chemotherapy, radiation, or both depends on the stage of the disease. More than 90% of patients diagnosed early can be cured, as can many with advanced disease.

Answer 5

Hodgkin's and Non-Hodgkin's Lymphoma: Differences and Similarities

Both Hodgkin's disease (sometimes referred to as Hodgkin's lymphoma) and non-Hodgkin's lymphoma are cancers that originate in a type of white blood cell known as a lymphocyte, an important component of the body's immune system. Both of these malignancies may cause similar symptoms, but the conditions themselves are different. The distinction between Hodgkin's disease and non-Hodgkin's lymphoma is made upon examination of the cancerous material (from a biopsy or aspiration of the tumor tissue). The type of abnormal cells identified in the sample determines whether a lymphoma is classified as Hodgkin's disease or non-Hodgkin's lymphoma.

Non-Hodgkin's lymphoma is much more common than Hodgkin's disease. In the United States, non-Hodgkin's lymphoma is the sixth most common cancer among males and the fifth most common cancer among females. Furthermore, the incidence of non-Hodgkin's lymphoma has been steadily increasing over the last decades. Non-Hodgkin's lymphoma is actually a heterogeneous group of over 30 types of cancers with differences in the microscopic appearance and biological characterization of the malignant lymphocytes. The different types of non-Hodgkin's lymphoma also have differences in their biologic behavior (such as the tendency to grow aggressively) that affect a patient's overall outlook (prognosis).

Hodgkin's disease is much less common than non-Hodgkin's lymphoma and accounts for only about 1% of all cancers in the U.S. The incidence of this cancer has actually been declining in recent years, in contrast to the increases in non-Hodgkin's lymphoma. The diagnosis of Hodgkin's disease is confirmed by visualizing tissue samples using a microscope.

You can get furthe details of the both dieses in detail from the following links -

http://www.mayoclinic.com/health/hodgkin...

http://www.mayoclinic.com/health/non-hod...