Question:

What is the effect of UV light on DNA structure?

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  1. Damage caused by exogenous agents comes in many forms. Some examples are:

    UV-B light causes crosslinking between adjacent cytosine and thymine bases creating pyrimidine dimers. This is called direct DNA damage.

    UV-A light creates mostly free radicals - especially if sunscreen penetrated into the skin. The damage caused by free radicals is called indirect DNA damage.


  2. dimerization of thymidine takes place by uv light

  3. as mentioned by others UV light causes dimerization of thymidines in DNA   T=T   . This dimers are repaired in what is known as dark repair..but excessive dimerization /chronic and total make repair more and more difficult which can lead to mutation and misreading of DNA.

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