Question:

What is the purpose of Fresh Frosen Plasma (FFP) when the anaesthetist askes to bring it?

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I mean

what is the function of FFD , and what does it do to our body ?

I know there is another thing which is called (concentrated RBC)

But I want the function of this , please

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4 ANSWERS


  1. As others have said, FFP is the part of the blood that has the clotting factors in it.  When we've given a lot of crystalloid (normal saline, lactated Ringer's sln, etc), we dilute the clotting factors in the blood.

    FFP helps replace those factors, and at the same time, gives more intravascular volume to the patient.  (There is debate as to whether colloids like FFP stay intravascular longer than crystalloids.  Clinically, they seem to work a little better, at least in the short term)

    Hope that helps.


  2. In surgery, it would be used in massive blood loss to replenish stores of clotting factors. It'll also act as a volume expander, but that's a side benifit, and it wouldn't be used primarily for that purpose.

    There are also a few people on warfarin who have been grossly overcoagulated and have a bleeding problem. FFP would be used pre-operatively, or at least begun there, in the case of emergent surgery.

  3. FFP is usually given to lower a persons clotting time.  It is given because it is full of clotting factors or as a volume expander.  People that might need it are those in coumadin toxicity (it will lower their INR), have a factor deficiency, those who have lost a alot of fluid volume in surgery (plus they will also get RBCs) and those that have had a massive blood transfusion (to get the plasma:cell ratio back to normal).

  4. FFP is the liquid part of blood - the concentrated RBC are the other part.

    It has the plasma proteins and the clotting factors - if someone recieves nothing but RBC and saline, the protein content of their blood goes too low ... then you give some FFP to increase the protein.

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