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What is the role of EDTA in DNA extraction from whole blood?

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What is the role of EDTA in DNA extraction from whole blood?

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  1. The EDTA is a chelating agent that ties up divalent metal ions; these ions are often cofactors necessary for the action of DNAses---enzymes present in the cell, which, when released by lysis along with the DNA, can degrade the DNA.

    http://www.waksmanfoundation.org/labs/wi...

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