What is the toxicity of diazinon in humans, typical of many organophosphates?

Question

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Answer 1

Diazinon Granules contain an organophosphate type of insecticide and as such are fairly toxic to non-target wildlife. Here are specific effects in humans, as per the link below.

EYES: The eye irritation potential of this substance has not been determined. However, it is not expected to cause eye irritation due to the granular formulation of this product. If eye contact occurs, eye irritation may include; discomfort, redness, swelling and blurred vision.

SKIN: This substance is not expected to cause prolonged or significant skin irritation. This substance can cause allergic skin reactions in some individuals. The dermal toxicity of this substance has not been determined. However, it may be slightly toxic to internal organs if absorbed through the skin. The degree of injury will depend on the amount absorbed.

INGESTION: Ingestion may cause irritation of the digestive tract which may include nausea, vomiting, and diarrhea. If swallowed, this substance is considered practically non-toxic to internal organs.

INHALATION: The systemic toxicity of this substance has not been determined. However, it should be practically non-toxic to internal organs if inhaled. This substance may be irritating if inhaled.

COMMENTS HEALTH: Depending upon the extent and degree of overexposure to the product, signs and symptoms of cholinesterase inhibition can result following either ingestion, skin contact or inhalation routes of exposure. Signs and symptoms of cholinesterase inhibition can result from either acute (one time), subchronic (repeated short-term) and chronic (daily life-time) overexposure to the product.

Signs and symptoms of cholinesterase inhibition usually occur within 12 hours following overexposure. These effects may include, but may not be limited to, headache, dizziness, weakness, nausea, vomiting, diarrhea, constriction of the pupil of the eye, blurred or dark vision, excessive salivation or nasal discharge, profuse sweating and abdominal cramps. Incontinence, unconsciousness, convulsions and breathing difficulties are indicative of severe poisoning. In untreated severe poisoning, death is due to respiratory failure or cardiac arrest.