What is zero integrated gel electrophoresis definition and use ?

Question

What is zero integrated gel electrophoresis definition and use ?

Answer 1

A form of Pulsed Field Electrophoresis for Separation of Large DNA.

Although the theory of pulsed field electrophoresis is a matter of debate, qualitative statements can be made about the movement of DNA in agarose gels during PFGE. During continuous field electrophoresis, DNA above 30-50 kb migrates with the same mobility regardless of size. This is seen in a gel as a single large diffuse band. If, however, the DNA is forced to change direction during electrophoresis, different sized fragments within this diffuse band begin to separate from each other.