What means gave europeans advantage over the indian tribes of the americas?

Question

What means gave europeans advantage over the indian tribes of the americas?

Answer 1

Externally, guns...

Internally, an immune system developed over thousands of years of living in close-quarters in Europe, and being offspring of many generations of ancestors that survived numerous plagues!

Answer 2

Superior numbers. They just kept coming.

Answer 3

I would say the means of transportation. The Europeans had large ships and horses.  The guns during that time were still primitive.  

Answer 4

First they had much more powerful weapons with longer range. second, they brought disease which they were immune to but the natives were not. lastly, they were there to get theirs where as the natives were more prone to keep the peace.