What proteins allow RBCs to perform their functions?

Question

What proteins allow RBCs to perform their functions?

Answer 1

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Answer 2

The primary function of the blood is the distribution of oxygen to the tissues, which is accomplished by the hemoglobin protein which binds oxygen. But other proteins are necessary for this to happen as well, such as glycoproteins on the surface of the red blood cell which keep them flowing freely.

"Effective function of the red blood cell depends on: [a] its strongly negative surface charge (derived from surface glycoproteins) which permits it to repulse other circulating cells, thereby preventing "clumping;" [2] its unique doughnut-like shape, which is rheologically highly efficient and permits rapid flow of the cells through capillaries; and [3] its ability to prevent oxidative stress to the hemoglobin molecule, thereby maintaining the four iron atoms on each hemoglobin molecule in the ferrous (Fe2+) state, in which configuration they are able to bind oxygen reversibly."