Question:

What three physical barriers are involved with the passage of materials during the urine filtration process?

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'Name one structural characteristic of each of the 3 barriers.

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  1. 1.Endothelial lining of capillaries in the glomerulus - 1 cell thick.

    2. Basement membrane - The basement membrane consists of an electron-dense membrane called the lamina densa, about 30–70 nanometers in thickness, and an underlying network of reticular collagen (type III) fibrils (its precursor is fibroblasts) which average 30 nanometers in diameter and 0.1–2 micrometers in thickness.

    3.Wall of Bowman's Capsule - A single layer of cells that forms from the renal tubule and surrounds the glomerulus. It forms the space where urine is collected after being filtered by the glomeruli before entering the tubules. Has podocytes.

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