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Where in the body is blood serum synthesized?

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Where in the body is blood serum synthesized?

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  1. There is no single serum factory, but a lot of the components are made in the liver.


  2. Serum refers to the antibody (which are proteins) portion of the blood. Antibodies are synthesized by B cells. B cells derive from bone marrow and enter the blood.

  3. First of all, the liquid that your blood cells float around in is called plasma, not serum. If you take some blood out and let it clot, then the liquid left over would be serum.

    Plasma is made of many things. It has lots of different proteins in it, like albumin and clotting factors. Most of them are made by the liver, but antibodies (also proteins) are made by B-cells (white blood cells). There are also salts (ions) - these originally come from your food, absorbed from your gut. Some of them, like calcium, might also come from your bones, your muscles or other places. There is also fat (lipid) and glucose in the plasma, which is either absorbed from the gut or made by the liver. There are also waste products in the plasma waiting to be excreted, such as bilirubin and urea, which are made by the liver, and creatinine, which comes from muscle. Of course it is all dissolved in water, which is absorbed from the gut.

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