Which antibiotics can pass BBB ( blood brain barrier ) ??? please i want accurate answer?

Question

i m asking about antibiotics can cross BBB to treat meningitis

Answer 1

Drug that cross BBB and used to treat meningitis:

1)  Cephalosporins:

eg. Ceftriaxone, Cefotaxime, ceftazidime, cefepime

2) Penicillins: Ampicillin

3) Antifungals: Amp B with flucytosine, Fluconazole

4) Vancomycin

5) Anti-tuberculous drugs. (eg. INH)

Answer 2

There are a large number of relatively lipophilic antibiotics but the most common antibiotics used are ampicillin, efotaxime, ceftriaxone, gentamicin sulfate, penicillin G and vancomycin. Ciprofloxacin and rifampin are also used rifampin is often used for children.

Antibiotics are usually given intravenously and the dose and duration depends on a number of factors.