Which is more effective for the treatment of insomnia: diphenhydramine (Benadryl) or doxylamine (Unisom)?

Question

Which is more effective for the treatment of insomnia: diphenhydramine (Benadryl) or doxylamine (Unisom)?

Answer 1

It might be different depending on the person, but personally, I have had far better results with doxylamine.  The diphenhydramine tends to wear off after a few hours and I lie there tossing and turning the rest of the night.  

You might have to experiment with how much doxylamine is best for you, though.  A whole Unisom pill is too much for me and leaves me feeling groggy the next day; I have to cut them in half.  :-)