Why arn't germ-line cells used for nuclear transfer in cloning?

Question

I am doing a research assignment on cloning. Two facts I have read are that:

1. Germ-line cells are the only somatic cells that have not gone through differentiation.

2. that it is an obstacle in cloning that cells differentiate.

All examples of nuclear transfer cloning I have read about have used a nucleus taken from a non- germ line cell.

Wouldn't it make sense / be easier, to use a nucleus taken from a germ-line cell, as the cell has not differentiated?

Any shared knowledge would be appreciated.

Answer 1

Germ cell lines are only haploid, that is they only have half the total number of chromosomes required for a fully functioning organism.

Briant Burke, MD

www.naturopathix.com