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Why do auto-antibodies develop and begin to destroy the body's own cells?

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Why do auto-antibodies develop and begin to destroy the body's own cells?

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  1. Your antibodies do not recognize the cells as part of your body and attack it as though it were a virus.  Happens when you get transplants and whatnot.


  2. The causes of autoantibody production are varied and not well understood. It is thought that some autoantibody production is due to a genetic predisposition combined with an environmental trigger (such as a viral illness or a prolonged exposure to certain toxic chemicals). There is generally not a direct genetic link however. While families may be susceptible to autoimmune conditions, individual family members may have different autoimmune disorders, or may never develop an autoimmune condition. Researchers believe that there may also be a hormonal component as many of the autoimmune conditions are much more prevalent in women of childbearing age.

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