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Why is an increase in the permeability of capillaries essential to the inflammatory response?

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Why is an increase in the permeability of capillaries essential to the inflammatory response?

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  1. allows the bodies defense mediators to travel from the bloodstream to the site of infection, to leak out of the capillaries; e.g. the macrophages, platelets, etc.


  2. So that the leukocytes(first are neutrophils) and other proteins could enter the site of infection--a process known as diapedesis or emigration.

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