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a. Lack of oxygen signals the genes in the nucleus to start the fermentation process. b. Cellular respiration simply stops at the lactate mid-product and does not proceed any further. c. The backlog of ADP causes the pyruvate to produce ATP directly. d. There is more pyruvate than the preparation reaction can oxidize; this uses NADH and regenerates NAD+ which pick up more electrons and keep glycolysis operating. e. Pyruvate is always reduced to lactate but this is the only process left when oxygen is not available.
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