Wich is the origin of epixiban and rivaroxaban, direct factor X inhibitors? How were they discovered?

Question

Wich is the origin of epixiban and rivaroxaban, direct factor X inhibitors?

They come from leeches?

Answer 1

The drug you're referring to is actually Apixaban. It is very new and the research is limited. http://www.ncbi.nlm.nih.gov/pubmed/17868...

Rivaroxaban: http://en.wikipedia.org/wiki/Rivaroxaban

This neatly explains the somewhat loose relationship between leeches and the modern medications you've mentioned:

http://www.medscape.com/viewarticle/5539...