Would taking 2 paracetamol 4 hours before drinking affect you?

Question

I have been told you can't drink and take paracetamol but surely 2 paracetamol 4 hours before you drink wouldn't affect you.

Answer 1

Alcohol and Paracetamol don't interact so you can even take it during your drinking sessions as long as you have gaps of four hours between each dose and don't take any more than 8 tablets in 24 hours.

The only types of Paracetamol I would not advise taking with alcohol is the ones with added codeine e.g. Co Codamol and Co Dydramol as the sedating effects of the codeine will be increased with booze.

And finally there is a prescription only Paracetamol mixed  tablet called Co Proxamol or other name Distalgesic one where alcohol is definitely NOT recommended, it will make you very dizzy and your will vomit for sure !   I have been there and got the flamin'  T-shirt .

Have great time but dont over do it,  that is the best advice  x  

Answer 2

no...it will be fine....4hours before drinking...it will be almost out of your system by then...that's why you are allowed to take more tablets after 4hours...don't worry!

Answer 3

It's ok as the two don't interact

Answer 4

Chronic excessive alcohol consumption can induce CYP2E1, thus increasing the potential toxicity of paracetamol. Whether chronic alcoholism should be considered a risk factor has been debated by some clinical toxicologists. Additionally, it appears acute alcohol ingestion at the time of a paracetamol overdose may have a protective effect.

Fasting is a risk factor, possibly because of depletion of hepatic glutathione reserves. It is well documented that concomitant use of the CYP2E1 inducer isoniazid increases the risk of hepatotoxicity, though whether 2E1 induction is related to the hepatotoxicity in this case is unclear. Concomitant use of other drugs that induce CYP enzymes such as antiepileptics (including carbamazepine, phenytoin, and barbiturates) have also been reported as risk factors.